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Xylazine and Medetomidine Are Rewriting What Overdose Looks Like. Naloxone Reverses the Opioid and the Patient Still Will Not Wake Up.

Xylazine and Medetomidine Are Rewriting What Overdose Looks Like. Naloxone Reverses the Opioid and the Patient Still Will Not Wake Up.

by Ethan Webb | Jul 24, 2026 | Technology

Veterinary sedatives like xylazine and the far stronger medetomidine now saturate the fentanyl supply, forcing SUD programs to rethink overdose response, withdrawal, and testing. Key Takeaways The opioid is no longer the whole overdose: Sedatives mixed into the...

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